Tuesday, February 14, 2012

bee venom

There are more than sixty identifiable components in bee venom.

Melittin- 50% of weight of dry venom.
Adolopin- 1%
Apamin- 3%
Peptide 401/Mast Cell Degranulating Peptide- 3%
Hyaluronidase- 3%
Phospholipase A2- 12%
Histamine- 0.9%

Activates immune system
Stimulates pituitary-cortical system secretion of cortisol
Immediate inflammatory effect
Secondary anti-Inflammatory effect
Improves blood circulation
Decreases sense of pain.

Honey bee venom contains at least 18 active substances. Melittin, the most prevalent substance, is one of the most potent anti-inflammatory agents known (100 times more potent than hydrocortisol). Adolapin is another strong anti-inflammatory substance, and inhibits cycooxygenase; it thus has analgesic activity as well. Apamin inhibits complement C3 activity, and blocks calcium-dependent potassium channels, thus enhancing nerve transmission. Other substances, such as Compound X, Hyaluronidase, Phospholipase A2, Histamine, and Mast Cell Degranulating Protein (MSDP), are involved in the inflammatory response of venom, with the softening of tissue and the facilitation of flow of the other substances. Finally, there are measurable amounts of the neurotransmitters, Dopamine, Norepinephrine and Seratonin.


Composition of Bee Venom


Bee Venom Collector, a product developed by Chung Jin Biotech, is designed to collect the bee venom by giving electro-stimulation to a live bee. From its world-class quality, it was awarded with a new device patent and a new technology certificate for its excellence.
As the technology has no substantial impact on previous bee-farming (collecting honey and pollen etc) and the living condition of the bee itself, it is a blue ocean creating a new source of income. The Bee Venom Collector by Chungjin Biotech can help you change your business. The core difference between Chungjin Biotech’s Bee Venom Collector over others lies in the low death rate of the bees. It has 12V input and output with a fuse that increases the safety. Moreover, a lamp has been installed as visual indicator for amateur users to be able to use with ease.
The machine is operated as following: Place the collecting plate horizontally leveled in front of the wooden beehive gate. Connect a battery to the controller and turn on the power when bees rest on the collecting plate. This will stimulates bees causing them to sting the glass plate and emit their venom. After a certain amount of time, turn off the power and dry the venom, and then separate the glass plate from the collecting plate and scrape the dried venom off with a scraper.
Bee-venom collected as such is often used for medicinal purposes. Bee-venom therapy that uses bees directly is not only inconvenient but also problematic for medical use, as the injection amount cannot be controlled. However, as the Bee Venom Collector can extract the venom from bees in a natural state, it is being greatly welcomed in medical field. As bee-farming industry is suffering from the saturated market with honey and other bee related products and declined production from climate change, the Bee Venom Collector by Chungjin Biotech is leading customers into a new market.
In the effort to create the world where human and nature can coexist, we succeeded in developing bee venom collector using solar cell. Upgrading from consumable batteries to semi-permanent solar cell, which is cost effective and easy to operate and manage from its reduced weight. A controller has been installed inside the bee venom collecting plate, which allows it to be installed on and off convenient in transportation. It is equipped with a display monitor that allows convenient operation through easy status check. By using the solar cell, the product helps to prevent excessive battery waste contributing for the welfare of human being and the environment.
A brand-new bee venom collector that helps you to maximize the venom collection with less effort. You can connect many frames at once and control by using one controller.

 

Chungjin Biotech guarantees the purity and the quality of the bee venom products as they are processed through strict refining process, which is being used in diverse fields.
Although the exact period of bee venom's origination is unknown, it has been passed down as a natural folk remedy for thousands of years. Also, Hippocrates, the Greek medical scientist also known as the father of medicine, left the record of using bee-sting. Bee venom is comprised of approximately 40 elements with 1.1313 density and 5.2 - 5.5 pH value. The key elements of bee venom are melittin, apamine, and MCD-peptide and others. It is known to be effective in pain relief, antiphlogistic, anti-bacteria, also accelerating blood circulation and hormone secretion from the pituitary gland.
Raw bee-venom has 1.3 density and 5.2 pH value with a bitter taste and light fragrant. 75% of raw bee-venom is protein, and the rest is composed of potassium, sodium, magnesium, phosphorus, alanine, valine, arginine, tryptophan, methionine, histidine, and other substances. When dried in room temperature, approximately 30% is left dried.
Traditionally, bee venom has been used for arthritis, inflammation in connective tissue or joints, and other pains. Moreover, it can be applied to rheumatoid arthritis, acute chronic arthritis, ruptured cervical or lumbar disc, spinal canal stenosis, fibromyalgia, myofascial pain, puerperal perspiration or arthralgia, a frozen shoulder, tennis elbow, and chronic sprain.
Additionally, bee-venom is effective in respiratory disease and diarrhea in pigs or calves, and when treated continuously until maturation, it increases the milk yield rate and antibiotic effect. Most previous antibiotics caused side effects from residue, but bee venom not only helps to safely raise livestock, but also supports to reduce the cost of disease control.
Melittin cell-liquefying-action (mitochondria, leukocyte, mast cell, and lysosome)
Apamine neuralgia relief, pain relief, anti-inflammatory, immunizing, and neurotoxic effects
Peptide MDC 401 anti-inflammatory action
Adolapin anti-inflammatory, pain relief, and fever alleviating effects
Inhibiteur de la protéase inhibits the dissolving of protein and ester and anti-inflammatory action
Secarpin hypothermia sedation
Procamine A, B X-ray protection
Hyaluronidase tissue breakdown and serotype substance
Phospholipase A2 breakdown of cell tissue, and hemolytic and catalytic action
Lysophospholipase increase in antibiotic role
Histamin depressant, intestinal contraction, and enhanced stomach acid secretion
Dopamine neurotransmitter
First developed in Korea by Chungjin Biotech, Honeybee Artificial Insemination Instrument is beneficial in improving the breeding by extracting sperm from drones and artificially inseminating to the queen.
Most apiaries are breeding honeybee by natural swarming and it causes genetic variation. The hives are becoming weaker and honey extracting is continually reducing. So, we need special technology to breed good species of honeybee: swarm control, disease-resistance, high honey production ability, queen bee breeding.
Natural mating occurs in midair by chance, it is irregular and hard to control. However, by using our artificial insemination instrument with high fertilization success rate, apiarists can breed improved species by themselves. The technology that can controls bee breed will open up new opportunities.
The operation of the machine is as following: Confine a queen bee for insemination in a plastic tube and anesthetize with carbon-dioxide. Then using a special syringe, extract sperm from drones. The process is completed once the extracted sperm is injected into the queen.
Honeybee is essential insect as they are major source for food and medicine as honey, pollen, royal jelly, propolis and venom. Thus, it is crucial to develop improved breed as it helps increase the quality and the harvest of agricultural products through pollen vector. This technology is inevitable in fostering the development of beekeeping industry.
We, Chung Jin Biotech Co., Ltd., have succeeded in developing a brand new instrument which adopting the electron microscope, lamp, monitor on previous Honeybee Artificial Insemination Instrument model.
Previous insemination instruments required a stereoscopic microscope and illuminator that caused operational and cost inefficiency. Moreover, inefficiency caused by ineffective technical educating system depending on individual physical condition and expertise was main obstacle.

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